HPV diseases and cervical cancer: Summing Up

Thursday 12 April 2018


8.00 Opening Lecture

8.20 Welcome P. Davies.-A. Frega - C. Gentili

ROOM A (Plenary session)

8.30 Opening Lecture
Chairman: G. Scambia | Speaker: W. Ricciardi
- HPV infection and carcinogenesis: a public health perspective.

8.50-10.20 HPV infection and Carcinogenesis
Chairpersons: P. Davies - A. Venuti | Speakers: J. Doorbar , B. Moscicki
- Human papillomavirus infection and the induction of neoplasia.
- The natural history of HPV infection in screening age women; do we have enough
data to really understand what is happening in this age group?
- Persistent vs repeated infections; can we tell the difference and does it make a
difference to cervical carcinogenesis?
- HPV infection in men; do we understand the natural history and clinical
implications for men and their partners?

10.20-11.00 Epidemiology of Cervical Cancer and HPV Infection
Chairpersons: A. Castanon – A.Lukic | Speakers: P. Davies, J. Dillner
- Cervical cancer trends around the world; are we making a difference?
- HPV vaccination and its impact on HPV infection rates around the world.

11.30-13.00 Cervical Screening
Chairpersons: J. Dillner- C. Gentili | Speakers: A. Castanon, P. Davies, M. Goodman
- The current status of cervical screening programmes around the world; are we
making progress where it is needed most or just improving the best?
- HPV testing for primary screening; who is doing what?
- The latest data from the HPV primary screening programmes; the benefits and the
challenges that remain to be solved.
- Cervical screening: is there still a role for the Pap test?


9.00-13.00 Free Communications
Chairpersons D. French - E. Giarnieri. - R.Senatori



14.30-15.40 Cervical Screening: the New Challenges
Chairpersons: A. Frega - U. Petry | Speakers: A. Castanon, M. Goodman, W. Huh
- Estimating the impact of HPV primary screening and HPV vaccination on cervical
cancer rates.
- The evolution of HPV testing in the USA.
- HPV screening recall and follow-up recommendations; do doctors stick to the rules?

15.40-16.50 HPV Positive, what Next?
Chairpersons: M. Cruickshan - M. Peroni | Speakers: P. Martin Hirsch, K.U. Petry
- HPV positive; what are the triage options and their associated risks.
- How does HPV status affect the treatment of low-grade cervical disease?
- Persistent HPV infection without colposcopically visible cervical disease: how
common and what is it the appropriate follow-up?

17.10-18.00 Colposcopy in the Era of HPV Vaccination and HPV Screening
Chairpersons: W. Huh - F. Sopracordevole | Speakers: M. Cruickshank, P. Martin Hirsch, K.U. Petry,
- The implications of HPV vaccination for the practice of colposcopy.
- HPV primary screening; will this affect the accuracy of colposcopy?
- Should colposcopists be re-trained to deal with the realities of the HPV era?

18.00-18.55 Noncompliance with Referral to Colposcopy
Chairpersons: P. Martin Hirsch - C. Zanardi | Speakers: M. Cruickshank, U. Tabuica, J. Waller
- Non compliance with colposcopy referral; the extent of the problem in different countries.
- Why do women decide not to go to colposcopy?
- Understanding and reducing the adverse psychological impact of colposcopy


14.30-16.00 Updates in Molecular Biology
Chairpersons: D. French - A. Venuti | Speakers: L. Dillner, J. Doorbar, B. Moscicki
- Latent papillomavirus infections: the role of the HPV test.
- Getting around in the molecular testing jungle: what clinicians and pathologists
should know to properly interpret the results.
- Investigating diagnostic problems of CIN1 and CIN2 associated with high-risk HPV by
combining the novel molecular biomarker PanHPVE4 with P16INK4a.
- The role of cytology and HPV genotyping in screening for anal cancer.

16.00-16.50 Updates in Cytopathology
Chairpersons: M. Benevolo – E. Giardini | Speakers: M.R. Giovagnoli, G. Negri
- Is the new Bethesda system tailored for HPV screening and molecular diagnosis?
- Cytology triage: what molecular testing cannot provide.

17.10-18.45 Ask the Experts
Coordinators : P. Davies- A. Frega- C. Gentili | Experts: J. Dillner, J.Doorbar, M. Goodman,
B. Moscicki, W. Prendiville, G. Negri
- Open forum: What would you like to ask a panel of experts?


Friday 13 April 2018


ROOM A (Plenary session)

8.30-10.30 Vaccination
Chairpersons: M. Cruickshank - A. Lukic | Speakers: R. De Vincenzo, J. Dillner,
L. Mariani, M. O'Connor, J. Waller
- HPV vaccination around the world today: the programs and the coverage rates.
- HPV vaccination; long-term efficacy and protection. What are the data?
- Screening in vaccinated and unvaccinated women: are two algorithms necessary
and if so how do we implement them?
- HPV vaccination of boys; who is doing what?
- Improving HPV vaccination coverage; what works and what doesn’t.
- The nonavalent HPV vaccine: what changes?

11.10-13.00 Ensuring the Safety and Effectiveness of Colposcopy

Chairpersons: A.Ciavattini - M. O'Connor | Speakers: M. Cruickshank, W. Huh,
P. Martin Hirsch, K.U. Petry, W Prendiville
- Treatment of cervical pre-cancer, current best practice
- Colposcopy training; the similarities and differences across Europe.
- Training colleagues in middle income countries
- Quality assurance of colposcopy; the European perspective
- Quality assurance of colposcopy; the American perspective.


8.30-13.00 Free Communications

Chairpersons: A. Biamonti- R. Barbero – E.Carico



14.30-15.30 Public Education and Coverage Rates
Chairpersons: F.Boselli - W.Prendiville | Speakers: M. Cruickshank, L. Dillner, M. O'Connor, J. Waller
- Social and psychological impact of HPV testing in cervical screening.
- Reaching under- or never-screened women; is self-sampling the answer?
- The impact of HPV vaccination on cervical cancer screening coverage; are the
predictions proving to be true?
- HPV vaccination for adolescents, Pap screening for under-30s, HPV screening for
over 30’s; how can we effectively communicate all this to ensure high programme

15.30 - 16.15 HPV and Vaginal Infection
Chairpersons: A. Biamonti - U. Tabuica | Speakers: F. De Seta, B. Moscicki
- The role of vaginal microbiome in HPV infection and disease.
- Chlamydia trachomatis infection: epidemiology, treatment and its role in HPV disease
- The effect of intrauterine devices on acquisition and clearance of human papillomavirus

16.15-16.55 Miscellanea
Chairpersons: R. Senatori- F. De Seta | Speakers : D. Caserta,W. Prendiville, U. Tabuica, F. Torcia
- HPV and fertility.
- Potential innovations in cervical precancer management
- The role of oral contraception and hormone replacement therapy in HPV infection
and disease.
- The ultrasound in the evaluation of preneoplastic and neoplastic lesions of the uterine cervix


14. 30 -15.20 Pap Smear: Never Say Never Again

Chairpersons: M. Benevolo – E. Carico | Speakers: W. Huh, G. Negri
- Don’t forget me: cytology of HPV negative lesions.
- What clinicians need from cytology.

15.20-17.20 The Cervical Cytopathology in the HPV Testing Era
Coordinators: M.R. Giovagnoli - G. Negri
- An interactive seminar slide of cervical cytopathology.

ROOM A (Plenary session)

Chairpersons: A. Frega – C. Gentili
17.20 Presentation of the Best 3 Free Communications and Award for the Best
17.50 General Discussion
18. 00 ECM Test
18.20 Prize giving for the three best speakers and conclusions



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